Establishment of an isothermal multiplex PCR for the diagnosis of vector borne diseases.

Health Partnerships – GlobalPaediatrics
The project of the Malaria Group at the University of Antioquia, Colombia, and the Paediatric Immunology Research Centre at the University Medical Centre Mainz is improving the diagnosis of acute viral syndrome in children. Problem: In Colombia there is a lack of the diagnostic capacities needed to identify specific pathogens that cause acute, non-specific fever syndromes. Inaccurate or incorrect diagnoses are an obstacle to making proper treatment decisions. Main activities: Test subjects are selected and blood specimens taken. Once equipment is procured it should be possible to conduct a PCR (polymerase chain reaction) analysis. PCR can be used to artificially reproduce DNA to identify diseases. Medical and scientific staff are trained in molecular-biology laboratory methods including PCR analysis. Short-term results: Blood specimens are taken from patients with acute fever syndromes, who are suspected of having contracted malaria or arbovirus. Molecular diagnoses of blood specimens taken from these patients can be produced. Long-term results: The clinical management of diseases caused by arbovirus or malaria is to be enhanced. More precise diagnosis and the targeted use of antibiotics and anti-malarial drugs are to reduce resistances within Colombian society.

You would like to find out more about the partnership project?
Get in touch with us.